Why Iverkor® Paste?
Iverkor Oral Paste for horses contains ivermectin, a unique broad-spectrum antiparasitic. Its convenience, broad-spectrum efficacy and wide safety margin make it an excellent antiparasitic product for horses. Contains proven ivermectin anthelmintic and boticide
For the treatment of parasitic infections due to internal parasites, including bots, in horses
ACTIVE INGREDIENT: Ivermectin 1.87% w/w
INTRODUCTION: Iverkor EQUELL Oral Paste for horses contains ivermectin, a unique broad-spectrum antiparasitic. Its convenience, broad-spectrum efficacy and wide safety margin make it an excellent antiparasitic product for horses.
PRODUCT DESCRIPTION: Iverkor Oral Paste is a clean, white, homogeneous, ready-to-use paste contained in a disposable plastic syringe.
INDICATIONS: Iverkor Oral Paste is indicated for the treatment of the following parasitic infections in horses:Large strongyles: adult and arterial stages of Strongylus vulgaris, and adult stage of S. edentatus, S. equinus and Triodontophorus spp.Small strongyles (including those resistant to certain benzimidazole class compounds): adult and luminal larval (L4) stages of Cyathostomum spp., Cylicocyclusspp., Cylicostephanus spp., Cylicodontophorus spp.Intestinal threadworms: adult stage of Strongyloides westeri.Pinworms: adults and luminal larval (L4) stages of Oxyuris equi.Ascarids: adults and developing larval (L3, L4) stages of Parascaris equorum.Hairworms: adult stage of Trichostrongylus axei.Large-mouth stomach worms: adult stage of Habronema muscae.Neck threadworms: microfilariae of Onchocerca cervicalis.Bots: oral and gastric stages of Gasterophilus intestinalis and G. nasalis.EQUELL Oral Paste is also indicated as an aid in the clinical improvement of dermatoses caused by cutaneous larvae of Habronema spp., Draschia megastoma, and microfilariae of Onchocerca cervicalis.Note to user – Healing of “Summer sores” caused by Habronema spp. and Draschia megastoma and involving extensive tissue changes may require other appropriate therapy in conjunction with treatment with EQUELL Oral Paste. Reinfection, and measures for its prevention, should also be considered. Consult your veterinarian if the condition does not improve.
DOSAGE: This syringe contains sufficient paste to treat one 600 kg horse at the recommended dose rate of 200 μg ivermectin/kg body weight. Each weight marking on the syringe plunger delivers enough paste to treat 100 kg body weight.
ADMINISTRATION: Iverkor Oral Paste is administered orally. (1) While holding plunger, turn the knurled ring on the plunger 1/4 turn to the left and slide it so the side nearest the barrel is at the prescribed weight marking. (2) Lock the ring in place by making a 1/4 turn to the right. (3) Make sure that the horse’s mouth contains no feed. (4) Remove the cover from the tip of the syringe. (5) Insert the syringe tip into the horse’s mouth at the space between the teeth. (6) Depress the plunger as far as it will go, depositing paste on the back of the tongue. (7) Immediately raise the horse’s head for a few seconds after dosing
MODE OF ACTION: Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class binds selectively and with high affinity to glutamate-gated-chloride ion channel which occur in invertebrate nerve and muscle cells. This leads to the increase of the permeability in the cell membrane to chloride ion with hyperpolarization of the nerve and muscle cells, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated-chloride channels, such as those gated by neurotransmitter gamma aminobutyric acid (GABA). Ivermectin has no measurable effect against flukes and tapeworms, presumably because they do not have GABA as a nerve impulse transmitte
The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamate-gated-chloride ion channels, macrocyclic lactones have a low affinity for other mammalian ligand-gated channels and they do not readily cross the blood brain barrier.
PRODUCT ADVANTAGES:
Broad-spectrum: Iverkor Oral Paste kills most important internal parasites, including bots and the arterial stages of S. vulgaris, with a single dose. Unique chemical compound: Iverkor Oral Paste contains a potent antiparasitic agent that is neither a benzimidazole nor an organophosphat